How often can you take ibuprofen and tylenol together

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When deciding what medication to use for pain management or fever reduction, many people turn to two of the best over-the-counter options: Tylenol (acetaminophen) and Advil or Motrin (ibuprofen). Both are available in name-brand or store-brand varieties, and the later work equally well.

Often, those looking for pain relief assume they must choose one medication or the other when, in fact, it is possible to use both medications together as each is processed differently by the body—acetaminophen is processed through the liver while ibuprofen clears through the kidneys. Additionally, studies have indicated that, when combined correctly, acetaminophen and ibuprofen provide greater relief than when used independently of one another.

For Adults and children over age 12

Researchers have recently investigated just how powerful the combination of acetaminophen and ibuprofen are in managing pain in adults. Studies indicate that, when combined, the two offer an equal  level of pain relief as opioid narcotics.

For children over the age of 12 and adults, both medications may be taken together at the same time. It is important to note the recommended dosage limits for adults and children over the age of 12:

  • 3,000 mg per day for acetaminophen
  • 1,200 mg per day for ibuprofen

In March of 2020, the FDA approved the first over-the-counter acetaminophen and ibuprofen combination drug in the U.S. Labeled Advil Dual Action, the medication is currently available at drugstores and grocery markets and contains 125mg of ibuprofen and 250mg of acetaminophen per tablet. Always read packaging labels and talk your doctor before starting a new medication.

The release of this drug is promising news as doctors look for alternatives to narcotics while the nation continues to battle the opioid epidemic.

For Fever Reduction in Children Under 12

When children experience fever, a caregiver’s first reaction is to try to eliminate it. While we want to offer medication that makes children more comfortable, it is important to remember that fever serves an important role in fighting infection. The presence of fever is a positive indication that the body’s immune response is working properly.

However, to provide comfort, choose either a children’s acetaminophen or ibuprofen and follow the dose directions on the back of the bottle. If one medication does not seem to work sufficiently to reduce fever or pain in children age 12 and under, the key is to alternate between acetaminophen and ibuprofen: administer one medication at 10 a.m., 2 p.m., and 6 p.m., and the other at 12 p.m., 4 p.m., and 8 p.m.

It is important to read the back of the package for dosing recommendations, and always check with your pediatrician before starting a new medication.

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Is it safe to take 2 ibuprofen and 2 Tylenol together?

Yes, you can safely take acetaminophen and ibuprofen together. And it may surprise you that taking these two medications together actually works better to relieve pain than taking them separately.

How far apart should you take Tylenol and ibuprofen?

Ibuprofen (Advil, Motrin) and acetaminophen (Tylenol) are over-the-counter pain relievers that work differently. It's generally safe to combine them as follows: Take ibuprofen and Tylenol together every 4 to 6 hours. Take ibuprofen and Tylenol alternating every 2 to 3 hours depending on the dose.

Can I alternate Tylenol and ibuprofen every 3 hours?

For very high or stubborn fevers, alternate between Acetaminophen and Ibuprofen every three hours (i.e., give a dose of Acetaminophen then three hours later give Ibuprofen then three hours later Acetaminophen, ect.) These two medications are safe to use together like this.

How often can you piggyback Tylenol and ibuprofen?

Doubling up on pain medications must be done carefully. Katherine Kazmier, M.D., a pediatrician with Seattle Children's Hospital, says it's generally safe to give both medications at the same time every six hours (always following dosing instructions on the bottle).

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