Neomycin and polymyxin b sulfates for ear infection

Pediotic Side Effects Center

What Is Pediotic?

Pediotic Suspension (neomycin and polymyxin B sulfates and hydrocortisone otic suspension) is a combination of antibiotics and a steroid used to treat ear infections caused by bacteria. Pediotic is available in generic form.

What Are Side Effects of Pediotic?

Common side effects of Pediotic include:

• temporary stinging or burning of your ear for a minute or two when applied

Tell your doctor immediately if you experience serious side effects of Pediotic, including hearing problems.

Pediotic may cause serious side effects including:

• hives,
• difficulty breathing,
• swelling of your face, lips, tongue, or throat,
• sever burning or other irritation after using the ear drops,
• hearing loss,
• skin rash, and
• redness, swelling, itching, dryness, scaling, or other irritation in or around the ear

Get medical help right away, if you have any of the symptoms listed above.

Seek medical care or call 911 at once if you have the following serious side effects:

• Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
• Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheartedness, or passing out;
• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

Dosage for Pediotic

For adults, the dose of Pediotic Suspension is 4 drops instilled into the affected ear 3 or 4 times daily. For infants and children, 3 drops are suggested because of the smaller capacity of the ear canal. Use for 10 consecutive days.

What Drugs, Substances, or Supplements Interact with Pediotic?

Pediotic Suspension may interact with other drugs. Tell your doctor all medications and supplements you use.

Pediotic During Pregnancy or Breastfeeding

During pregnancy, Pediotic Suspension should be used only if prescribed. It is unknown if this medication passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Pediotic Suspension (neomycin and polymyxin B sulfates and hydrocortisone otic suspension) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

Pediotic Consumer Information

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

• severe burning or other irritation after using the ear drops;
• hearing loss; or
• skin rash, redness, swelling, itching, dryness, scaling, or other irritation in or around the ear.

Common side effects may include:

• mild itching after using the ear drops.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SLIDESHOW

Pediotic Professional Information

SIDE EFFECTS

Neomycin occasionally causes skin sensitization. Ototoxicity and nephrotoxicity have also been reported (see WARNINGS). Adverse reactions have occurred with topical use of antibiotic combinations including neomycin and polymyxin B. Exact incidence figures are not available since no denominator of treated patients is available. The reaction occurring most often is allergic sensitization. In one clinical study, using a 20% neomycin patch, neomycin-induced allergic skin reactions occurred in two of 2,175 (0.09%) individuals in the general population.2 In another study, the incidence was found to be approximately 1%.3

The following local adverse reactions have been reported with topical corticosteroids, especially under occlusive dressings: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, and miliaria. Stinging and burning have been reported rarely when this drug has gained access to the middle ear.

Read the entire FDA prescribing information for Pediotic (Neomycin, Polymyxin B and Hydrocortisone)

© Pediotic Patient Information is supplied by Cerner Multum, Inc. and Pediotic Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.